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3' 5-Methyl dC

Return to Modified Bases Modifications

5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.

Scientific Details
MW:303.2
Mod Code:/3Me-dC/
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo 81,00 € EUR Add To Order
250 nmole DNA Oligo 100,00 € EUR Add To Order
1 umole DNA Oligo 131,00 € EUR Add To Order
2 umole DNA Oligo 164,00 € EUR Add To Order
5 umole DNA Oligo 263,00 € EUR Add To Order
10 umole DNA Oligo 541,00 € EUR Add To Order
100 nmole RNA Oligo 85,00 € EUR Add To Order
250 nmole RNA Oligo 100,00 € EUR Add To Order
1 umole RNA Oligo 131,00 € EUR Add To Order
5 umole RNA Oligo 263,00 € EUR Add To Order
10 umole RNA Oligo 541,00 € EUR Add To Order
Structure
Structure