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3' 5-Methyl dC

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5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.

Scientific Details
MW:303.2
Mod Code:/3Me-dC/
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo 80,00 € EUR Add To Order
250 nmole DNA Oligo 94,00 € EUR Add To Order
1 umole DNA Oligo 123,00 € EUR Add To Order
2 µmole DNA Oligo 154,00 € EUR Add To Order
5 umole DNA Oligo 247,00 € EUR Add To Order
10 umole DNA Oligo 509,00 € EUR Add To Order
100 nmole RNA Oligo 80,00 € EUR Add To Order
250 nmole RNA Oligo 94,00 € EUR Add To Order
1 umole RNA Oligo 123,00 € EUR Add To Order
5 umole RNA Oligo 247,00 € EUR Add To Order
10 umole RNA Oligo 509,00 € EUR Add To Order
Structure
Structure